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Cytokeratin 1 Antikörper (C-Term)

KRT1 Reaktivität: Human IHC (f) Wirt: Maus Monoclonal LHK1 unconjugated
Produktnummer ABIN6937639
  • Target Alle Cytokeratin 1 (KRT1) Antikörper anzeigen
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Bindungsspezifität
    • 20
    • 16
    • 16
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 87
    • 54
    • 41
    • 24
    • 16
    • 13
    • 8
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 70
    • 38
    • 1
    Maus
    Klonalität
    • 63
    • 46
    Monoklonal
    Konjugat
    • 46
    • 12
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Cytokeratin 1 Antikörper ist unkonjugiert
    Applikation
    • 78
    • 52
    • 30
    • 28
    • 27
    • 26
    • 22
    • 17
    • 17
    • 14
    • 13
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.
    Kreuzreaktivität (Details)
    Human. Rat.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    A 13-amino acid peptide (VRFVSTSYSGVTR) from the C-terminus of human KRT1 protein
    Klon
    LHK1
    Isotyp
    IgG2a kappa
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  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Skin or Cervix.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))
    Andere Bezeichnung
    KRT1 (KRT1 Produkte)
    Hintergrund
    67 kDa Cytokeratin, CK1, Cytokeratin-1, EHK1, Epidermolytic hyperkeratosis 1, EPPK, K1, Keratin Type II Cytoskeletal 1, Keratin-1, KRT1, KRT1A, NEPPK, Type II cytoskeletal 1, Type-II keratin Kb1,Cytokeratin 1 (Suprabasal Keratinocyte Marker)
    Cellular localisation: Cytoplasmic
    Molekulargewicht
    67kDa
    Gen-ID
    38748, 80828
    UniProt
    P04264
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