JUP Antikörper

Produktnummer ABIN6937613

Dieser Maus Monoklonal Antikörper detektiert spezifisch JUP in WB, IF, IHC, FACS und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Huhn, Hund, Rind (Kuh) und Cat.

Kurzübersicht für JUP Antikörper (ABIN6937613)

Target: JUP (Junction Plakoglobin (JUP))

Reaktivität: Human, Maus, Ratte, Huhn, Hund, Rind (Kuh), Cat

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser JUP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS), ELISA

Klon: 15F11

Produktdetails anti-JUP Antikörper

Verwendungszweck: Catenin, gamma (Cardiomyocyte Marker) Antibody

Spezifität: It recognizes a protein of 80-87 kDa, identified as gamma-catenin. The catenins (°™, æ, Á and 79oΩL) are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. °™ T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantly expressed in cardio-myocytes and in the peritubular myoid cells of the testis. °™ T-catenin binds to °™ E-catenin as well as to æ-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for °™-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer s disease (LOAD) as well as to dilated cardiomyopathy.

Kreuzreaktivität (Details): Human. Mouse. Cat. Rat. Chicken. Cow. Dog.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant, full length chicken Catenin gamma protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, SK-BR3, A431, HT20, 293, HepG2, A549 or MCF-7 cells. Skin.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu JUP

Target: JUP (Junction Plakoglobin (JUP))

Andere Bezeichnung: JUP

Hintergrund:

ARVD12, Catenin (cadherin-associated protein), gamma 80 kDa, Catenin gamma, CTNNG, Desmoplakin III, Desmoplakin-3, DP3, DPIII, Junction Plakoglobin, PDGB, PKGB

HeLa, SK-BR3 or MCF-7 cells.

Molekulargewicht: 80-87kDa

Gen-ID: 3728, 514174

UniProt: P14923

Pathways: Cell-Cell Junction Organization, Maintenance of Protein Location