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Rekombinanter IGHG Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IGHG in IHC (f). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6937496

Kurzübersicht für Rekombinanter IGHG Antikörper (ABIN6937496)

Target

IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 15
  • 2
Human

Wirt

  • 8
  • 7
  • 2
Maus

Klonalität

  • 15
  • 2
Monoklonal

Konjugat

  • 15
  • 1
  • 1
Dieser IGHG Antikörper ist unkonjugiert

Applikation

  • 11
  • 11
  • 7
  • 7
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon

RIG266
  • Spezifität

    Recognizes a protein of 75kDa, identified as gamma heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant full-length human IGHG protein

    Isotyp

    IgG1 kappa
  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

    Andere Bezeichnung

    IGHG

    Hintergrund

    G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1/2/3/4 Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4, Immunoglobulin Heavy Constant 1/2/3/4,IgG (Immunoglobulin Gamma Heavy Chain) (B-Cell Marker)
    Cellular localisation: Cytoplasm, Cell Surface and Secreted

    Molekulargewicht

    75kDa

    Gen-ID

    3500, 3501, 3502

    UniProt

    P01857, P01859, P01860, P01861
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