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IGHG Antikörper

Der Maus Monoklonal Anti-IGHG-Antikörper wurde für FACS, IF und IHC (f) validiert. Er ist geeignet, IGHG in Proben von Human zu detektieren.
Produktnummer ABIN6937494

Kurzübersicht für IGHG Antikörper (ABIN6937494)

Target

IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

Reaktivität

  • 15
  • 2
Human

Wirt

  • 8
  • 7
  • 2
Maus

Klonalität

  • 15
  • 2
Monoklonal

Konjugat

  • 15
  • 1
  • 1
Dieser IGHG Antikörper ist unkonjugiert

Applikation

  • 11
  • 10
  • 7
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon

IG217-IG266
  • Spezifität

    This MAb is specific to heavy chain of IgG and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Gamma heavy chain(IgG1, IgG2a, IgG2b, IgG3). The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Ab-3 is superb for staining of formalin-fixed tissues.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Purified human IgG

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    Known_Application: Flow Cytometry (1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: 293T, Raji or hPBL cells. Tonsil or Spleen.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    IGHG (Immunoglobulin Heavy Chain (Gamma Polypeptide) (IGHG))

    Andere Bezeichnung

    IGHG

    Hintergrund

    G1m Marker, G2m Marker, G3m Marker, G4m Marker, HDC, Heavy Chain Disease Protein, Human Immunglobulin G, Ig gamma1/2/3/4 Chain C Region, IGHG1, IGHG2, IGHG3, IGHG4, Immunoglobulin Heavy Constant 1/2/3/4,Immunoglobulin Gamma (IgG) Heavy Chain
    Cellular localisation: Cytoplasm, Cell Surface and Secreted

    Molekulargewicht

    ~75kDa

    Gen-ID

    3500, 3501, 3502

    UniProt

    P01857, P01859, P01860, P01861
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