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GATA3 Antikörper (AA 357-436)

GATA3 Reaktivität: Human IHC (f) Wirt: Maus Monoclonal GATA3-2442 unconjugated
Produktnummer ABIN6937301
  • Target Alle GATA3 Antikörper anzeigen
    GATA3 (GATA Binding Protein 3 (GATA3))
    Bindungsspezifität
    • 33
    • 16
    • 15
    • 7
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 357-436
    Reaktivität
    • 119
    • 89
    • 9
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Human
    Wirt
    • 104
    • 35
    • 2
    • 1
    Maus
    Klonalität
    • 94
    • 48
    Monoklonal
    Konjugat
    • 74
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser GATA3 Antikörper ist unkonjugiert
    Applikation
    • 90
    • 45
    • 32
    • 27
    • 27
    • 19
    • 19
    • 17
    • 10
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    GATA-3 is a zinc finger transcription factor and plays an important role in promoting and directing cell proliferation, development, and differentiation in many tissues and cell types. GATA-3 expression is primarily seen in breast and urothelial carcinomas.'Therefore, GATA3 antibody can be useful in the identification of unknown primary carcinoma when carcinomas of the breast or bladder are a possibility.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant fragment of human GATA3 protein (around aa 357-436) (exact sequence is proprietary)
    Klon
    GATA3-2442
    Isotyp
    IgG2b kappa
    Top Product
    Discover our top product GATA3 Primärantikörper
  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: MCF-7 or T47D cells. Breast or Bladder Carcinoma.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    GATA3 (GATA Binding Protein 3 (GATA3))
    Andere Bezeichnung
    GATA3 (GATA3 Produkte)
    Hintergrund
    GATA3, GATA binding protein-3, GATA-binding factor 3, GATA3, HDR, HDRS, Transacting T-cell-specific transcription factor GATA-3,GATA-3 (Breast and Urothelial Marker)
    Cellular localisation: Nuclear
    Molekulargewicht
    50kDa
    Gen-ID
    2625, 524134
    UniProt
    P23771
    Pathways
    Hormone Transport, Regulation of Hormone Metabolic Process, Tube Formation
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