Rekombinanter Frataxin Antikörper (AA 57-210)
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- Target Alle Frataxin (FXN) Antikörper anzeigen
- Frataxin (FXN)
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- AA 57-210
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Frataxin Antikörper ist unkonjugiert
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Applikation
- ELISA, Coating (Coat)
- Spezifität
- Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)
- Klon
- RFXN-2124
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product FXN Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- Frataxin (FXN)
- Andere Bezeichnung
- FXN (FXN Produkte)
- Synonyme
- zgc:158218 antikoerper, LOC100284365 antikoerper, BcDNA:AT09528 antikoerper, CG8971 antikoerper, DFH antikoerper, Dfh antikoerper, Dmel\\CG8971 antikoerper, X25 antikoerper, dfh antikoerper, CyaY antikoerper, FA antikoerper, FARR antikoerper, FRDA antikoerper, RGD1565754 antikoerper, Frda antikoerper, frataxin antikoerper, fxn antikoerper, LOC100284365 antikoerper, TVAG_182150 antikoerper, fh antikoerper, FTX1 antikoerper, FXN antikoerper, Fxn antikoerper
- Hintergrund
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CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25,Frataxin (Mitochondrial Marker)
Cellular localisation: Cytoplasmic (Mitochondria) - Molekulargewicht
- 14kDa
- Gen-ID
- 2395, 20685
- UniProt
- Q16595
- Pathways
- Transition Metal Ion Homeostasis, Regulation of Cell Size
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