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Rekombinanter Frataxin Antikörper (AA 57-210)

FXN Reaktivität: Human ELISA, Coat Wirt: Maus Monoclonal rFXN-2124 unconjugated Recombinant Antibody
Produktnummer ABIN6937290
  • Target Alle Frataxin (FXN) Antikörper anzeigen
    Frataxin (FXN)
    Antikörpertyp
    Recombinant Antibody
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 57-210
    Reaktivität
    • 63
    • 22
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 58
    • 12
    Maus
    Klonalität
    • 60
    • 10
    Monoklonal
    Konjugat
    • 39
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Frataxin Antikörper ist unkonjugiert
    Applikation
    • 54
    • 38
    • 21
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Coating (Coat)
    Spezifität
    Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)
    Klon
    RFXN-2124
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product FXN Primärantikörper
  • Applikationshinweise

    Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Optimal dilution for a specific application should be determined.

    Positive_Control: HepG2, HL-60 or HEK293 cells. Pancreas and Liver.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    Frataxin (FXN)
    Andere Bezeichnung
    FXN (FXN Produkte)
    Synonyme
    zgc:158218 antikoerper, LOC100284365 antikoerper, BcDNA:AT09528 antikoerper, CG8971 antikoerper, DFH antikoerper, Dfh antikoerper, Dmel\\CG8971 antikoerper, X25 antikoerper, dfh antikoerper, CyaY antikoerper, FA antikoerper, FARR antikoerper, FRDA antikoerper, RGD1565754 antikoerper, Frda antikoerper, frataxin antikoerper, fxn antikoerper, LOC100284365 antikoerper, TVAG_182150 antikoerper, fh antikoerper, FTX1 antikoerper, FXN antikoerper, Fxn antikoerper
    Hintergrund
    CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25,Frataxin (Mitochondrial Marker)
    Cellular localisation: Cytoplasmic (Mitochondria)
    Molekulargewicht
    14kDa
    Gen-ID
    2395, 20685
    UniProt
    Q16595
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Cell Size
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