FTL Antikörper (AA 38-165)
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- Target Alle FTL Antikörper anzeigen
- FTL (Ferritin, Light Polypeptide (FTL))
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Bindungsspezifität
- AA 38-165
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser FTL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Coating (Coat)
- Spezifität
- Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa 38-165) of human FTL protein (exact sequence is proprietary)
- Klon
- FTL-1386
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product FTL Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Immunohistology (Formalin-fixed) (0.25-0.5 μg/mL for 30 min at RT) (Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes) Optimal dilution for a specific application should be determined.
Positive_Control: HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Kidney, Cerebellum or Testis.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- FTL (Ferritin, Light Polypeptide (FTL))
- Andere Bezeichnung
- FTL (FTL Produkte)
- Synonyme
- NBIA3 antikoerper, apoferritin antikoerper, ferritin antikoerper, fhc antikoerper, fth antikoerper, fth1 antikoerper, fthl6 antikoerper, ftn-2 antikoerper, pig15 antikoerper, plif antikoerper, FT antikoerper, Ftl antikoerper, Ftl-1 antikoerper, L-ferritin antikoerper, FTL antikoerper, Ftl1 antikoerper, FTL2 antikoerper, FTD antikoerper, ferritin light chain antikoerper, ferritin, heavy polypeptide 1 L homeolog antikoerper, ferritin light polypeptide 1 antikoerper, ferritin, light polypeptide antikoerper, ferritin light-chain antikoerper, ferritin light chain 1 antikoerper, FTL antikoerper, fth1.L antikoerper, Ftl1 antikoerper, CpipJ_CPIJ004069 antikoerper, Ftl antikoerper
- Hintergrund
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Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3,Ferritin, Light Chain (Node-Negative Breast Tumor Prognostic Marker)
Cellular localisation: Cytoplasmic - Molekulargewicht
- 19-25kDa
- Gen-ID
- 2512, 433670
- UniProt
- P02792
- Pathways
- Transition Metal Ion Homeostasis
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