FGA Antikörper

Produktnummer ABIN6937227

Der Maus Monoklonal anti-FGA Antikörper wird verwendet zum Nachweis von FGA in Proben von Human. Er wurde validiert für ELISA, IF und FACS.

Kurzübersicht für FGA Antikörper (ABIN6937227)

Target: FGA (Fibrinogen alpha Chain (FGA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGA Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: UC45

Produktdetails anti-FGA Antikörper

Verwendungszweck: Fibrinogen Alpha Chain Antibody

Spezifität: The plasma glycoprotein Fibrinogen is synthesized in the liver and comprises three structurally different subunits: . Fibrinogen is important in platelet aggregation, the final step of the coagulation cascade (i.e. the formation of Fibrin) and determination of plasma viscosity and erythrocyte aggregation. It is both constitutively expressed and inducible during an acute phase reaction. Hemostasis following tissue injury deploys essential plasma procoagulants (Prothrombin and Factors X, IX, V and VIII), which are involved in a blood coagulation cascade leading to the formation of insoluble Fibrin clots and the promotion of platelet aggregation. Following vascular injury, Fibrinogen is cleaved by Thrombin to form Fibrin, which is the most abundant component of blood clots. The cleavage products of Fibrinogen regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab purified by Protein L.

Immunogen: Human acute monoblastic leukemia cells.

Isotyp: IgM, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: Plasma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10  mM PBS with 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu FGA

Target: FGA (Fibrinogen alpha Chain (FGA))

Andere Bezeichnung: FGA

Hintergrund:

Ac1873, Fba5e, FGA, Fib, Fib2, Fibrinogen alpha chain, Fibrinogen, A alpha polypeptide, Fibrinogen--alpha polypeptide chain, Fibrinopeptide A

Plasma.

Molekulargewicht: 30kDa

Gen-ID: 2243, 351593

UniProt: P02671