F13A1 Antikörper (AA 46-181)

Produktnummer ABIN6937204

Dieses Anti-F13A1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von F13A1 in WB, ELISA, IF, FACS, Coat und IHC (f). Geeignet für Human.

Kurzübersicht für F13A1 Antikörper (AA 46-181) (ABIN6937204)

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser F13A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Klon: F13A1-1448

Produktdetails anti-F13A1 Antikörper

Bindungsspezifität: AA 46-181

Spezifität: The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. It recognizes a protein of 83 kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment of human Factor XIIIa protein (aa46-181) (exact sequence is proprietary)

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: 293T cells. Placenta.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu F13A1

Target: F13A1 (Coagulation Factor XIII, A1 Polypeptide (F13A1))

Andere Bezeichnung: F13A1

Hintergrund: Coagulation factor XIII A chain, Coagulation factor XIII A1 polypeptide, Coagulation factor XIIIa, F13A, F13a1, Factor XIIIA, Fibrin stabilizing factor, A subunit, Fibrinoligase, FSF, A subunit, Protein-glutamine gamma-glutamyltransferase A chain, TGase, Transglutaminase A chain, Transglutaminase. plasma,Factor XIIIa (Coagulation Factor XIIIA Chain)
Cellular localisation: Cytoplasmic and Secreted

Molekulargewicht: 83kDa

Gen-ID: 2162, 335513

UniProt: P00488