Ezrin Antikörper
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- Target Alle Ezrin (EZR) Antikörper anzeigen
- Ezrin (EZR)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Ezrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Ezrin, Moesin and Radixin belong to a family of highly homologous actin-associated proteins that are localized just beneath the plasma membrane. The proteins are believed to be involved in the mediation of interactions between cytoskeletal and membrane proteins. Ezrin serves as a major cytoplasmic substrate of various protein-tyrosine kinases, including the epidermal growth factor receptor. Ezrin has also been identified as a cAMP-dependent protein kinase (A-kinase) anchoring protein and designated AKAP78. Moesin and Radixin share over 70 % homology with Ezrin and are co-expressed within various cell types. Despite the high degree of homology, the three proteins exhibit a distinct receptor-specific pattern of phosphorylation. Overexpression of Ezrin predicts the poor prognosis of gastric adenocarcinoma.
- Kreuzreaktivität (Details)
- Human. Others-not tested.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human full-length Ezrin protein
- Klon
- CPTC-Ezrin-1
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product EZR Primärantikörper
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- Applikationshinweise
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Known_Application: Western Blotting (1-2 μg/mL), ,Immunohistology (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: SKBr3, HeLa, HEK293, MCF-7, Jurkat, A431, MCF-7. Cerebral cortex and hippocampus.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- Ezrin (EZR)
- Andere Bezeichnung
- Ezrin (EZR Produkte)
- Synonyme
- CVIL antikoerper, CVL antikoerper, VIL2 antikoerper, ezr antikoerper, vil2 antikoerper, wu:fc05c03 antikoerper, wu:fj31d06 antikoerper, cvil antikoerper, cvl antikoerper, Vil2 antikoerper, AW146364 antikoerper, R75297 antikoerper, p81 antikoerper, ezr.S antikoerper, ezrin antikoerper, ezrin b antikoerper, ezrin L homeolog antikoerper, EZR antikoerper, ezrb antikoerper, ezr antikoerper, Ezr antikoerper, ezr.L antikoerper
- Hintergrund
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Villin-2, CVIL, Epididymis secretory protein Li 105, EZR, p81, VIL2, Cytovillin, Cytovillin 2, HEL S 105, DKFZp762H157,Ezrin / p81
Cellular localisation: Cell Surface - Molekulargewicht
- 87kDa
- Gen-ID
- 7430, 487027
- UniProt
- P15311
- Pathways
- Maintenance of Protein Location
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