ENAH Antikörper (AA 485-589)

Produktnummer ABIN6937147

Der Maus Monoklonal anti-ENAH Antikörper (Klon ENAH-1988) (ABIN6937147) detektiert spezifisch ENAH in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für ENAH Antikörper (AA 485-589) (ABIN6937147)

Target: ENAH (Enabled Homolog (ENAH))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ENAH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Klon: ENAH-1988

Produktdetails anti-ENAH Antikörper

Bindungsspezifität: AA 485-589

Verwendungszweck: ENAH / MENA (Actin Regulator) Antibody

Spezifität: The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)

Isotyp: IgG2c, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: MCF-7 cells. Uterus.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu ENAH

Target: ENAH (Enabled Homolog (ENAH))

Andere Bezeichnung: ENAH

Hintergrund:

ENA, ENAH, MENA, NDPP1

MCF-7 cells. Uterus.

Molekulargewicht: 80/88/140kDa

Gen-ID: 55740, 497893

UniProt: Q8N8S7