ENAH Antikörper (AA 485-589)
Kurzübersicht für ENAH Antikörper (AA 485-589) (ABIN6937147)
Target
Alle ENAH Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 485-589
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Spezifität
- The Wiskott-Aldrich syndrome (WAS) is characterized by thrombocytopenia, eczema, defects in cell-mediated and humoral immunity and a propensity for lymphoproliferative diseases. The syndrome is the result of a mutation in the gene encoding a proline-rich protein termed WASP. WASP is a downstream effector of Cdc42 and has been implicated in actin polymerization and cyto- skeletal organization. Distantly related proteins, VASP (vasodilator-stimulated phosphoprotein) and Mena (for mammalian enabled protein), are involved in the regulation of cytoskeletal dynamics. Both Mena and VASP accumulate at focal adhesions. Mena is highly expressed in the developing nervous system and may be involved in growth cone motility and axon guidance.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant fragment of human MENA protein (around aa 485-589) (exact sequence is proprietary)
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Isotyp
- IgG2c kappa
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Applikationshinweise
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Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: MCF-7 cells. Uterus.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- ENAH (Enabled Homolog (ENAH))
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Andere Bezeichnung
- ENAH
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Hintergrund
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ENA, ENAH, MENA, NDPP1,ENAH / MENA (Actin Regulator)
Cellular localisation: Cytoplasmic -
Molekulargewicht
- 80/88/140kDa
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Gen-ID
- 55740, 497893
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UniProt
- Q8N8S7
Target
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