Desmoglein 3 Antikörper (AA 379-491)
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- Target Alle Desmoglein 3 (DSG3) Antikörper anzeigen
- Desmoglein 3 (DSG3)
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Bindungsspezifität
- AA 379-491
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Desmoglein 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Coating (Coat)
- Spezifität
- Recognizes a protein of 130 kDa, identified as Desmoglein-3 (DSG3). This MAb is highly specific to Desmoglein-3 and does not cross-react with other members of the Desmoglein-family. DSG3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Research has shown that DSG3 has a very high sensitivity (80 % ) and specificity (100 %) in recognizing squamous cell carcinoma (SqCC). Therefore, DSG3 is considered a very important marker for lung SqCC and can be a useful ancillary marker to separate SqCC from other subtypes of lung cancer. Moreover, studies have shown that DSG3 expression in lung SqCC may indicate a poor prognosis.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa 379-491) human DSG3 protein (exact sequence is proprietary)
- Klon
- DSG3-2796
- Isotyp
- IgG2b kappa
- Top Product
- Discover our top product DSG3 Primärantikörper
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anti-Desmoglein 3 (DSG3) (AA 55-159) antibody
DSG3 Reaktivität: Human WB, ELISA, IHC, FACS Wirt: Maus Monoclonal 6G2C11 unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human IHC, StM Wirt: Maus Monoclonal DSG3-2840 unconjugated
anti-Desmoglein 3 (DSG3) (AA 858-999) antibodyDSG3 Reaktivität: Human WB, ELISA, IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human IHC Wirt: Maus Monoclonal MSVA-543M unconjugated
anti-Desmoglein 3 (DSG3) (AA 70-615) antibodyDSG3 Reaktivität: Human ELISA, IF, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 50-75) antibodyDSG3 Reaktivität: Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 379-491) antibodyDSG3 Reaktivität: Human WB, ELISA, Coat Wirt: Maus Monoclonal DSG3-2796 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reaktivität: Human WB, IF, IHC, FACS, StM Wirt: Maus Monoclonal 5G11 unconjugated
anti-Desmoglein 3 (DSG3) antibodyDSG3 Reaktivität: Human WB, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Desmoglein 3 (DSG3) (AA 334-604) antibodyDSG3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C8 unconjugated
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- Applikationshinweise
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Known_Application: ELISA (For coating, order Ab without BSA), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: A431 cells. Skin or Lung Squamous Cell Carcinoma (SCC).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- Desmoglein 3 (DSG3)
- Andere Bezeichnung
- DSG3 (DSG3 Produkte)
- Synonyme
- DSG3 antikoerper, CDHF6 antikoerper, PVA antikoerper, bal antikoerper, balding antikoerper, desmoglein 3 antikoerper, DSG3 antikoerper, Dsg3 antikoerper
- Hintergrund
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130 kDa pemphigus vulgaris antigen (PVA), Balding (Bal), Cadherin family member 6 (CDHF6), Desmoglein-3 (DSG3),Desmoglein-3 (Squamous Cell Marker)
Cellular localisation: Cell Surface - Molekulargewicht
- 130kDa
- Gen-ID
- 1830, 1925
- UniProt
- P32926
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