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DBN1 Antikörper (AA 150-281)

DBN1 Reaktivität: Human WB, IHC (f) Wirt: Maus Monoclonal DBN1-2879 unconjugated
Produktnummer ABIN6937083
  • Target Alle DBN1 Antikörper anzeigen
    DBN1 (Drebrin 1 (DBN1))
    Bindungsspezifität
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 150-281
    Reaktivität
    • 36
    • 20
    • 19
    • 1
    • 1
    Human
    Wirt
    • 28
    • 8
    • 1
    Maus
    Klonalität
    • 28
    • 9
    Monoklonal
    Konjugat
    • 21
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DBN1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 13
    • 13
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
    Klon
    DBN1-2879
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product DBN1 Primärantikörper
  • Applikationshinweise

    Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: PC3 cells. Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    DBN1 (Drebrin 1 (DBN1))
    Andere Bezeichnung
    DBN1 (DBN1 Produkte)
    Synonyme
    D0S117E antikoerper, DBN1 antikoerper, LOC733967 antikoerper, drebrin 1 antikoerper, drebrin 1 S homeolog antikoerper, DBN1 antikoerper, Dbn1 antikoerper, dbn1.S antikoerper, dbn1 antikoerper
    Hintergrund
    Developmentally regulated brain protein, Drebrin 1, Drebrin, Drebrin E, Drebrin E2, Drebrin1, DrebrinE,Drebrin 1 (DBN1)
    Cellular localisation: Cytoplasmic
    Molekulargewicht
    120kDa
    Gen-ID
    1627, 130316
    UniProt
    Q16643
    Pathways
    Maintenance of Protein Location
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