DBN1 Antikörper (AA 150-281)
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- Target Alle DBN1 Antikörper anzeigen
- DBN1 (Drebrin 1 (DBN1))
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Bindungsspezifität
- AA 150-281
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser DBN1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- Drebrins (developmentally regulated brain proteins) are cytoplasmic proteins that bind F-actin in the brain and are involved in cell migration, extension of neuronal processes and plasticity of dendrites. There are three isoforms: two embryonic types (E1 and E2), and an adult type (A), generated by alternative RNA splicing from a single Drebrin gene. Drebrins are expressed mainly in brain neurons but are also found in skeletal muscle, heart, placenta, pancreas and kidney. Drebrin has been designated as a marker of the dendritic spine. Decreases in Drebrin levels in the brain have been been associated with Alzheimer s disease and Down syndrome.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (aa 150-281) of human DBN1 protein (exact sequence is proprietary)
- Klon
- DBN1-2879
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product DBN1 Primärantikörper
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- Applikationshinweise
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Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: PC3 cells. Brain neurons. Also found in the heart, placenta, skeletal muscle, kidney and pancreas.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- DBN1 (Drebrin 1 (DBN1))
- Andere Bezeichnung
- DBN1 (DBN1 Produkte)
- Synonyme
- D0S117E antikoerper, DBN1 antikoerper, LOC733967 antikoerper, drebrin 1 antikoerper, drebrin 1 S homeolog antikoerper, DBN1 antikoerper, Dbn1 antikoerper, dbn1.S antikoerper, dbn1 antikoerper
- Hintergrund
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Developmentally regulated brain protein, Drebrin 1, Drebrin, Drebrin E, Drebrin E2, Drebrin1, DrebrinE,Drebrin 1 (DBN1)
Cellular localisation: Cytoplasmic - Molekulargewicht
- 120kDa
- Gen-ID
- 1627, 130316
- UniProt
- Q16643
- Pathways
- Maintenance of Protein Location
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