P-Cadherin Antikörper

Produktnummer ABIN6936895

Produktdetails anti-P-Cadherin Antikörper

Target: P-Cadherin (CDH3)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser P-Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Spezifität: Recognizes a protein of 116 kDa, identified as P-Cadherin-1 (CDH3). Itis a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congenital hypotrichosis with juvenile macular dystrophy.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant human P-cadherin fusion protein

Klon: 12H6

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL) Optimal dilution for a specific application should be determined.

Positive_Control: A431 or PC-3 cells. Pancreas, Placenta or Prostate.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu P-Cadherin

Target: P-Cadherin (CDH3)

Andere Bezeichnung: CDH3 (CDH3 Produkte)

Synonyme: CDH3 antikoerper, Cadherin-3 antikoerper, AI385538 antikoerper, Cadp antikoerper, Cdhp antikoerper, P-cadherin antikoerper, Pcad antikoerper, CDHP antikoerper, HJMD antikoerper, PCAD antikoerper, E-Cad antikoerper, E-cadherin antikoerper, EP-cadherin antikoerper, XTCAD-1 antikoerper, c-cadherin antikoerper, cadherin-1 antikoerper, cdh1 antikoerper, cdh1-b antikoerper, cdh3 antikoerper, cdhc-A antikoerper, cdhp antikoerper, hjmd antikoerper, l-cam antikoerper, lcam antikoerper, pcad antikoerper, uvo antikoerper, uvomorulin antikoerper, xb-cad antikoerper, xcdh1 antikoerper, CDH15 antikoerper, K-CAM antikoerper, cadherin 3 antikoerper, cadherin 3 L homeolog antikoerper, Cadherin-3 antikoerper, CDH3 antikoerper, Cdh3 antikoerper, cdh3.L antikoerper, cdh-3 antikoerper

Hintergrund: Cadherin 3 type 1, Cadherin-3, Cadp, Calcium dependent adhesion protein placental, CDH3, CDHP, HJMD, P-cadherin (Placental), PCAD, Placental cadherin,P-Cadherin (CDH3)
Cellular localisation: Cell surface

Molekulargewicht: 116kDa

Gen-ID: 1001, 191842

UniProt: P22223