CD68 Antikörper
Kurzübersicht für CD68 Antikörper (ABIN6936787)
Target
Alle CD68 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- This antibody recognizes a glycoprotein of 110 kDa, which is identified as CD68. It is important for identifying macrophages in tissue sections. It stains macrophages in a wide variety of human tissues, including Kupffer cells and macrophages in the red pulp of the spleen, in lamina propria of the gut, in lung alveoli, and in bone marrow. It reacts with myeloid precursors and peripheral blood granulocytes. It also reacts with plasmacytoid T cells, which are supposed to be of monocyte/macrophage origin. It shows strong granular cytoplasmic staining of chronic and acute myeloid leukemia and also reacts with rare cases of true histiocytic neoplasia. Lymphomas are negative or show few granules.
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Keine Kreuzreaktivität
- Huhn, Hund, Schwein
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Kreuzreaktivität (Details)
- Human. Monkey. Mouse. Rat. Rabbit. Cat. Does not react with Pig, Dog or Chicken.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Subcellular fraction of human alveolar macrophages
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Isotyp
- IgG1 kappa
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Applikationshinweise
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Tonsil, Lymph Node or Spleen.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- CD68 (CD68 Molecule (CD68))
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Andere Bezeichnung
- CD68
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Hintergrund
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GP110, LAMP4, Microsialin, Macrosialin, SCARD1, Scavenger Receptor Class D Member-1,CD68 (Macrophage Marker)
Cellular localisation: Cell Surface and Cytoplasmic -
Molekulargewicht
- 110kDa
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Gen-ID
- 968, 647419
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UniProt
- P34810
Target
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