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CD6 Antikörper

CD6 Reaktivität: Human FACS, IF, IHC (f) Wirt: Maus Monoclonal 3F7B5 unconjugated

Produktnummer ABIN6936765

Datenblatt (PDF)

Target Alle CD6 Antikörper anzeigen

CD6
Reaktivität
83

29

21

1

1

1

1
Human
Wirt
52

36

4
Maus
Passende Sekundärantikörper
Klonalität
58

34
Monoklonal
Konjugat
38

8

7

7

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser CD6 Antikörper ist unkonjugiert
Applikation
55

51

33

18

17

15

11

8

5

4

3

2

1
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität

CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular scavenger receptor cysteine-rich (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.

Kreuzreaktivität (Details)

Human.

Aufreinigung

1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen

Human rheumatoid synovial T cell line ST-1

Klon

3F7B5

Isotyp

IgG1 kappa

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anti-CD6 (CD6) antibody
CD6 Reaktivität: Human FACS, IF, IHC, StM Wirt: Maus Monoclonal 3F7B5 unconjugated

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anti-CD6 (CD6) antibody (PE)
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Applikationshinweise

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: MOLT-4, CCRF-CEM, Jurkat cells, Tonsil.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Konzentration

1.0 mg/mL

Buffer

Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel

Azide free

Lagerung

-20 °C,-80 °C

Informationen zur Lagerung

Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit

24 months
Target

CD6

Andere Bezeichnung

CD6 (CD6 Produkte)

Synonyme

TP120 antikoerper, OX52 antikoerper, CD6 antigen antikoerper, CD6 molecule antikoerper, Cd6 molecule antikoerper, Cd6 antikoerper, CD6 antikoerper

Hintergrund

T12, TP120,CD6 (Negative Marker of T-regulatory Cells)
Cellular localisation: Cell surface and cytoplasmic

Molekulargewicht

90-130kDa

Gen-ID

923, 744366

UniProt

P30203