CD4 Antikörper

Produktnummer ABIN6936702

Der Maus Monoklonal anti-CD4 Antikörper wird verwendet zum Nachweis von CD4 in Proben von Human. Er wurde validiert für FACS und ELISA.

Kurzübersicht für CD4 Antikörper (ABIN6936702)

Target: CD4

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA

Klon: C4-206

Produktdetails anti-CD4 Antikörper

Verwendungszweck: CD4 (T-Helper/Inducer Cell Marker) Antibody

Spezifität: Recognizes a protein of 55 kDa, identified as CD4. CD4 is a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigens and is also a receptor for the human immunodeficiency virus. This protein is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human CD4 protein

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (0.5-2 μg/million cells), ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: Human peripheral blood mononuclear cells (PBMCs), CCRF-CEM or HL-60. Lymph node or tonsil.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Hintergrund:

L3T4, Leu3, Ly-4, Lymphocyte antigen CD4, p55, T cell antigen T4/LEU3, T cell differentiation antigen L3T4, T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

CCRF-CEM or HL-60. Lymph node or tonsil., Human peripheral blood mononuclear cells (PBMCs)

Molekulargewicht: 55kDa

Gen-ID: 920, 631659

UniProt: P01730

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events