CD4 Antikörper

Produktnummer ABIN6936701

Dieser Ratte Monoklonal Antikörper detektiert spezifisch CD4 in FACS, IF, ELISA, Neut und Coat. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für CD4 Antikörper (ABIN6936701)

Target: CD4

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Neutralization (Neut), Coating (Coat)

Klon: GK1-5

Produktdetails anti-CD4 Antikörper

Keine Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A/G

Immunogen: Mouse CTL clone V4

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: Spleen, Thymus or Lymph Node.

Known Application: ELISA (For coating, order Ab without BSA & Azide), Neutralization Studies (Order Ab without BSA & Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 10 mM PBS without BSA and without Azide.

Konservierungsmittel: Azide free

Lagerung: 4 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.

Haltbarkeit: 24 months

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4

Hintergrund: CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.

Molekulargewicht: 55kDa

Gen-ID: 12504

UniProt: P06332

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events