CD28 Antikörper
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- Target Alle CD28 Antikörper anzeigen
- CD28
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD28 Antikörper ist unkonjugiert
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Applikation
- ELISA, Coating (Coat)
- Spezifität
- Recognizes a glycoprotein of 44-88 kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
- Kreuzreaktivität (Details)
- Human.
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant human CD28 protein
- Klon
- C28-77
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD28 Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (For coating, order Ab without BSA), Optimal dilution for a specific application should be determined.
Positive_Control: Jurkat cells. Human lymph nodes and tonsils.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- CD28
- Andere Bezeichnung
- CD28 (CD28 Produkte)
- Synonyme
- Tp44 antikoerper, CD28RNA antikoerper, cd28 antikoerper, CD28 molecule antikoerper, CD28 antigen antikoerper, Cd28 molecule antikoerper, CD28 molecule L homeolog antikoerper, CD28 antikoerper, Cd28 antikoerper, cd28.L antikoerper
- Hintergrund
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T-cell-specific surface glycoprotein CD28, Tp44,CD28
Cellular localisation: Cell Surface - Molekulargewicht
- 44kDa (monomer), 88kDa (dimer)
- Gen-ID
- 940, 591629
- UniProt
- P10747
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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