Rekombinanter CD207 Antikörper (AA 74-213)

Produktnummer ABIN6936636

Produktdetails anti-CD207 Antikörper

Target: CD207 (CD207 Molecule, Langerin (CD207))

Antikörpertyp: Recombinant Antibody

Bindungsspezifität: AA 74-213

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Coating (Coat)

Spezifität: Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2+-dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)

Klon: RLGRN-1821

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or A549 cells (WB).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: CD207 (CD207 Produkte)

Synonyme: CD207 antikoerper, CLEC4K antikoerper, RGD1565913 antikoerper, CD207 molecule antikoerper, CD207 antigen antikoerper, CD207 antikoerper, Cd207 antikoerper

Hintergrund: C-type lectin domain family 4 member K, CD207, CLEC4K, Langerhans cell specific c type lectin, Langerin,Langerin / CD207 (Marker of Langerhans Cells)
Cellular localisation: Cell surface and cytoplasmic

Molekulargewicht: 48kDa

Gen-ID: 50489, 199731

UniProt: Q9UJ71