Annexin a1 Antikörper

Produktnummer ABIN6936420

Produktdetails anti-Annexin a1 Antikörper

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Annexin a1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Spezifität: The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Mixture of native proteins from human bone tissues

Klon: 5E4-1

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: A431 and K562 cell lysates. Human esophagus, placenta and prostate tissues.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu Annexin a1

Target: Annexin a1 (ANXA1) (Annexin A1 (ANXA1))

Andere Bezeichnung: ANXA1 (ANXA1 Produkte)

Synonyme: anx1a antikoerper, anxa1 antikoerper, wu:fa01d11 antikoerper, wu:fa05d11 antikoerper, wu:fk69h01 antikoerper, MGC64363 antikoerper, anx1 antikoerper, lpc1 antikoerper, MGC89164 antikoerper, ANXA1 antikoerper, ANX1 antikoerper, LPC1 antikoerper, p35 antikoerper, Anx-1 antikoerper, Anx-A1 antikoerper, C430014K04Rik antikoerper, Lpc-1 antikoerper, Lpc1 antikoerper, Anx1 antikoerper, annexin A1a antikoerper, annexin A1 antikoerper, annexin A1 L homeolog antikoerper, Annexin A1 antikoerper, anxa1a antikoerper, anxa1 antikoerper, anxa1.L antikoerper, ANXA1 antikoerper, LOC100335033 antikoerper, Anxa1 antikoerper

Hintergrund: ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35,Annexin A1 / (Hairy Cell Leukemia Marker)
Cellular localisation: Nuclear and Cytoplasmic

Molekulargewicht: 35kDa

Gen-ID: 301, 494173

UniProt: P04083

Pathways: Hormone Transport