ALPL Antikörper

Produktnummer ABIN6936394

Dieses Anti-ALPL-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ALPL in FACS, IF und IHC (fro). Geeignet für Rind (Kuh).

Kurzübersicht für ALPL Antikörper (ABIN6936394)

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Reaktivität: Rind (Kuh)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ALPL Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: V17-1

Produktdetails anti-ALPL Antikörper

Spezifität: There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to hypo-phosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms. Alternatively spliced transcript variants, which encode the same protein, have been identified for this gene.

Kreuzreaktivität (Details): Human. Cow.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Bovine intestinal alkaline phosphatase

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Frozen) (1-2 μg/mL for 30 minutes at RT)Optimal dilution for a specific application should be determined.

Positive_Control: Intestine.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu ALPL

Target: ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))

Andere Bezeichnung: ALPL

Hintergrund: Alkaline phosphatase, germ cell, Alkaline phosphatase, testicular and thymus, Alkaline phosphatase liver/bone/kidney, Alkaline phosphatase, tissue-nonspecific, ALPG, ALPL, Germ cell alkaline phosphatase, Testicular and thymus alkaline phosphatase, Tissue non-specific alkaline phosphatase, Tissue nonspecific ALP (TNAP or TNSALP),Alkaline Phosphatase (Tissue-Nonspecific)
Cellular localisation: Cell Surface

Molekulargewicht: 55kDa

Gen-ID: 249, 75431

UniProt: P05186