ALDH1A1 Antikörper (AA 315-434)

Produktnummer ABIN6936385

Produktdetails anti-ALDH1A1 Antikörper

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Bindungsspezifität: AA 315-434

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ALDH1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Spezifität: ALDH1A1 belongs to the ALDH enzymes, a family of evolutionarily conserved enzymes comprised of 19 isoforms that are localized in the cytoplasm, mitochondria or nucleus. ALDH1A1 is predominantly expressed in the epithelium of testis, brain, eye, liver, kidney, as well as neural and hematopoietic stem cells. Reportedly, high ALDH1A1 expression is found in solitary fibrous tumor (SFT) and hemangiopericytoma (HPC), compared to meningiomas and synovial sarcomas. In combination with CD34, ALDH1A1 may be useful for the differentiation among SFT, HPC, meningioma, and synovial sarcoma.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (around aa 315-434) of human ALDH1A1 protein (exact sequence is proprietary).

Klon: ALDH1A1-1381

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Western Blot (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

Positive_Control: Liver, K562, Lung, HepG2 or A549 cells. Colon or Testicular Carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu ALDH1A1

Target: ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))

Andere Bezeichnung: ALDH1A1 (ALDH1A1 Produkte)

Synonyme: ALDC antikoerper, ALDH-E1 antikoerper, ALDH1 antikoerper, ALDH11 antikoerper, PUMB1 antikoerper, RALDH1 antikoerper, AL1A1 antikoerper, aldc antikoerper, aldh-e1 antikoerper, aldh1 antikoerper, aldh11 antikoerper, pumb1 antikoerper, raldh1 antikoerper, GGADHR antikoerper, ALDH1A1 antikoerper, ALDDH antikoerper, Ahd2 antikoerper, Aldh1 antikoerper, Aldh2 antikoerper, Ahd-2 antikoerper, Aldh1a2 antikoerper, E1 antikoerper, Raldh1 antikoerper, Aldh1a1 antikoerper, ALHDII antikoerper, RALDH 1 antikoerper, RalDH1 antikoerper, aldehyde dehydrogenase 1 family member A1 antikoerper, aldehyde dehydrogenase 1 family, member A1 antikoerper, aldehyde dehydrogenase 1 family member A1 L homeolog antikoerper, aldehyde dehydrogenase family 1, subfamily A1 antikoerper, aldehyde dehydrogenase antikoerper, retinal dehydrogenase 1 antikoerper, ALDH1A1 antikoerper, aldh1a1 antikoerper, Aldh1a1 antikoerper, aldh1a1.L antikoerper, aldH1 antikoerper, LOC100732581 antikoerper, LOC101822890 antikoerper

Hintergrund: Acetaldehyde dehydrogenase 1, AHD2, ALDC, Aldehyde dehydrogenase 1 soluble, Aldehyde dehydrogenase 1A1, Aldehyde dehydrogenase family 1 member A1, ALDH-E1, ALDH1, ALDH1A1, epididymis luminal protein 12, epididymis luminal protein 9, epididymis secretory sperm binding protein Li 53e, HEL-S-53e, PUMB1, RALDH1, Retinal dehydrogenase 1,ALDH1A1 (Aldehyde Dehydrogenase 1A1)
Cellular localisation: Cytoplasmic

Molekulargewicht: 56kDa

Gen-ID: 216, 76392

UniProt: P00352

Pathways: Dopaminergic Neurogenesis