CD20 Antikörper (PE)
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- Target Alle CD20 (MS4A1) Antikörper anzeigen
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD20 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)
- Spezifität
- Recognizes a protein of 33-37 kDa, identified as CD20 (Workshop V, Code CD20.12). B9E9 recognizes extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting B cells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in B-cell activation and cell cycle progression.
- Aufreinigung
- Purified by Protein A/G
- Immunogen
- Lymphoblastoid cell line Daudi
- Klon
- B9E9
- Isotyp
- IgG2a kappa
- Top Product
- Discover our top product MS4A1 Primärantikörper
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- Applikationshinweise
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Positive Control: Daudi, Raji and U266 and human lymphocytes.
Known Application: Flow Cytometry: 5 µL per test per one million cells (or 5 µL per 100 µL of whole blood)Immunofluorescence (1:50-1:100)Optimal dilution for a specific application should be determined.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 100 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA and 0.05 % azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Haltbarkeit
- 24 months
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- Target
- CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))
- Andere Bezeichnung
- MS4A1 (MS4A1 Produkte)
- Synonyme
- B1 antikoerper, Bp35 antikoerper, CD20 antikoerper, CVID5 antikoerper, LEU-16 antikoerper, MS4A2 antikoerper, S7 antikoerper, AA960661 antikoerper, Cd20 antikoerper, Ly-44 antikoerper, Ms4a2 antikoerper, MS4A1 antikoerper, bp35 antikoerper, cd20 antikoerper, ms4a2 antikoerper, leu-16 antikoerper, ms4a4c antikoerper, cd20-like antikoerper, membrane spanning 4-domains A1 antikoerper, membrane-spanning 4-domains, subfamily A, member 1 antikoerper, B-lymphocyte antigen CD20 antikoerper, MS4A1 antikoerper, Ms4a1 antikoerper, ms4a1 antikoerper, LOC101694281 antikoerper
- Molekulargewicht
- 33-37kDa
- Gen-ID
- 931
- UniProt
- P11836
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