HIV-1 p24 Antikörper (CF®488A)

Produktnummer ABIN6933792

Produktdetails anti-HIV-1 p24 Antikörper (CF®488A)

Target: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Reaktivität: Human Immunodeficiency Virus (HIV)

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HIV-1 p24 Antikörper ist konjugiert mit CF®488A

Applikation: Immunofluorescence (IF), Immunocytochemistry (ICC)

Aufreinigung: Purified by Protein A/G

Immunogen: Recombinant HIV-1 Gag p24 protein

Klon: HIV1-24-661

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Positive Control: HIV-1 infected cells. Tissues.

Known Application: Immunocytochemistry (Acetone or paraformaldehyde fixed) (1:50-1:100),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 100 μg/mL

Buffer: 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 4 to 8°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu HIV-1 p24

Target: HIV-1 p24 (Human Immunodeficiency Virus 1 Capsid (HIV-1 p24))

Andere Bezeichnung: Human Immunodeficiency Virus Type-1 p24 (HIV1-p24) (HIV-1 p24 Produkte)

Substanzklasse: Viral Protein

Hintergrund: Human immunodeficiency virus (HIV) is a retrovirus that causes acquired immune deficiency syndrome (AIDS), a condition in humans in which the immune system begins to fail, leading to life-threatening opportunistic infections. HIV mainly infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. Two species of HIV infect humans: HIV-1 and HIV-2, with HIV-1 being the more virulent strain. The gag gene of human immunodeficiency virus 1 (HIV-1) encodes a precursor protein known as Pr55Gag. The viral protease PR cleaves this precursor to generate p17, p24, p7, and p6 proteins, which are required for virus particle assembly. HIV-1 Gag p24 is a capsid protein that constitutes the core of AIDS virus HIV-1. p6 and p7 are the components of the nucleocapsid, and p17 provides a protective matrix. HIV-1 Gag p24 is indispensable to the reproduction of AIDS virus and constitutes an essential element for the AIDS virus particle construction. As this protein is detectable from the early stage of AIDS virus infection, its measurement is commonly used as an indicator of HIV-1 infection and viral load.

Molekulargewicht: 24kDa (mature), 55kDa & 41kDa (precursors)

Gen-ID: 155348

UniProt: P04585