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CEACAM1/5 Antikörper (CF®488A)

Dieses Anti-CEACAM1/5-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von CEACAM1/5 in FACS, IF und T. Geeignet für Human.
Produktnummer ABIN6933700

Kurzübersicht für CEACAM1/5 Antikörper (CF®488A) (ABIN6933700)

Target

CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

Reaktivität

Human

Wirt

  • 7
  • 5
Maus

Klonalität

  • 10
  • 2
Monoklonal

Konjugat

  • 12
Dieser CEACAM1/5 Antikörper ist konjugiert mit CF®488A

Applikation

  • 7
  • 6
  • 6
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF), Test (T)

Klon

C66-1009
  • Spezifität

    This antibody recognizes proteins of 80-200 kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70 % are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.

    Kreuzreaktivität (Details)

    Human,

    Aufreinigung

    Antibody Purified from Bioreactor Concentrate by Protein A/G and conjugated to various reporter molecules.

    Immunogen

    Recombinant full-length human CEA protein

    Isotyp

    IgG2a
  • Applikationshinweise

    Positive Control: MCF7 or 293T cells. Colon carcinoma.

    Known Application: Flow Cytometry (5 µL per test per one million cells or 5 µL per 100 µL of whole blood),Immunofluorescence (1:50-1:100),Optimal dilution for a specific application should be determined.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    100 μg/mL

    Buffer

    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

    Haltbarkeit

    24 months
  • Target

    CEACAM1/5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1/5 (CEACAM1/5))

    Andere Bezeichnung

    CEACAM1 & CEACAM5

    Hintergrund

    Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1),Carcinoembryonic Antigen (CEA) / CD66
    Cellular localisation: Cytoplasmic and luminal surface

    Molekulargewicht

    80-200kDa

    Gen-ID

    1048, 634, 709196

    UniProt

    P06731
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