VPS35 Antikörper (Biotin)
Kurzübersicht für VPS35 Antikörper (Biotin) (ABIN6932992)
Target
Alle VPS35 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Spezifität
- Ubiquitous. Highly expressed in brain, colon, heart, kidney, ovary, placenta, skeletal muscle, small intestine, testis, thymus.,Detects ~92 kDa.
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Protein G Purified
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Immunogen
- Full length recombinant human VSP35
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Isotyp
- IgG2a
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Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:200)
- IP (1:200)
- optimal dilutions for assays should be determined by the user.
- optimal dilutions for assays should be determined by the user.
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Kommentare
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A 1:1000 dilution of ABIN6932992 was sufficient for detection of VPS35 in 10 μg of SH-SY5Y by ECL immunoblot analysis using Goat Anti-Mouse IgG:HRP as the secondary antibody.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol, 0.09 % Sodium azide, Storage buffer may change when conjugated
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- VPS35 (Vacuolar Protein Sorting 35 (VPS35))
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Andere Bezeichnung
- VPS35
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Hintergrund
- Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson's Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).
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Gen-ID
- 55737
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NCBI Accession
- NP_060676
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UniProt
- Q96QK1
Target
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