CD63 Antikörper (AA 101-200)

Produktnummer ABIN687742

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch CD63 in FACS, WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc) und IF (p). Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für CD63 Antikörper (AA 101-200) (ABIN687742)

Target: CD63

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD63 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-CD63 Antikörper

Bindungsspezifität: AA 101-200

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD63

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CD63 Antikörper (ABIN687742)

Del Pozo-Acebo, Hazas, Tomé-Carneiro, Gil-Cabrerizo, San-Cristobal, Busto, García-Ruiz, Dávalos: "Bovine Milk-Derived Exosomes as a Drug Delivery Vehicle for miRNA-Based Therapy." in: International journal of molecular sciences, Vol. 22, Issue 3, (2021) (PubMed).

Marzesco, Flötenmeyer, Bühler, Obermüller, Staufenbiel, Jucker, Baumann: "Highly potent intracellular membrane-associated Aβ seeds." in: Scientific reports, Vol. 6, pp. 28125, (2016) (PubMed).

Sun, Zhao, Li, Wang, Nie, Peng, Wang, Zhang, Tian, Li, Song, Wang, Xu, Tian, Zhao, Xu, Zhong, Han, Ling, Chang, Li: "Osteoclast-derived microRNA-containing exosomes selectively inhibit osteoblast activity." in: Cell discovery, Vol. 2, pp. 16015, (2016) (PubMed).

Son, Rahimian, Shin, Siltanen, Patel, Revzin: "Microfluidic compartments with sensing microbeads for dynamic monitoring of cytokine and exosome release from single cells." in: The Analyst, (2015) (PubMed).

Details zu CD63

Target: CD63

Andere Bezeichnung: CD63/MLA1

Hintergrund:

Synonyms: MLA1, ME491, LAMP-3, OMA81H, TSPAN3, CD63 antigen, Granulophysin, Lysosomal-associated membrane protein 3, Melanoma-associated antigen ME491, Ocular melanoma-associated antigen, Tetraspanin-3, Tspan-3, CD63

Background: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.

Gen-ID: 967

UniProt: P08962