RBBP6 Antikörper (AA 2-150) (Cy7)
Kurzübersicht für RBBP6 Antikörper (AA 2-150) (Cy7) (ABIN687208)
Target
Alle RBBP6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - AA 2-150
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Kreuzreaktivität
 - Maus, Ratte
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Homologie
 - Human
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Aufreinigung
 - Purified by Protein A.
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Immunogen
 - KLH conjugated synthetic peptide derived from human P2PR
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Isotyp
 - IgG
 
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Applikationshinweise
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                        IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - 1 μg/μL
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Buffer
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
 - ProClin
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Vorsichtsmaßnahmen
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
 - 12 months
 
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- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
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Andere Bezeichnung
 - Rbbp6/P2p-R
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Hintergrund
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Synonyms: PACT, MY038, P2P-R, RBQ-1, SNAMA, E3 ubiquitin-protein ligase RBBP6, Proliferation potential-related protein, Protein P2P-R, Retinoblastoma-binding Q protein 1, Retinoblastoma-binding protein 6, p53-associated cellular protein of testis, RBBP6, P2PR, RBQ1
Background: E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53, may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth.
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Gen-ID
 - 5930
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UniProt
 - Q7Z6E9
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Pathways
 - Regulatorische RNA Pathways
 
Target
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