RBBP6 Antikörper (AA 2-150) (Cy5)
Kurzübersicht für RBBP6 Antikörper (AA 2-150) (Cy5) (ABIN687206)
Target
Alle RBBP6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 2-150
-
Kreuzreaktivität
- Maus, Ratte
-
Homologie
- Human
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- KLH conjugated synthetic peptide derived from human P2PR
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 μg/μL
-
Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))
-
Andere Bezeichnung
- Rbbp6/P2p-R
-
Hintergrund
-
Synonyms: PACT, MY038, P2P-R, RBQ-1, SNAMA, E3 ubiquitin-protein ligase RBBP6, Proliferation potential-related protein, Protein P2P-R, Retinoblastoma-binding Q protein 1, Retinoblastoma-binding protein 6, p53-associated cellular protein of testis, RBBP6, P2PR, RBQ1
Background: E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome. May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53, may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth.
-
Gen-ID
- 5930
-
UniProt
- Q7Z6E9
-
Pathways
- Regulatorische RNA Pathways
Target
-