TRAP1 Antikörper (AA 501-650)

Produktnummer ABIN686647

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TRAP1 in ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für TRAP1 Antikörper (AA 501-650) (ABIN686647)

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAP1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TRAP1 Antikörper

Bindungsspezifität: AA 501-650

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSP75

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TRAP1

Target: TRAP1 (TNF Receptor-Associated Protein 1 (TRAP1))

Andere Bezeichnung: HSP75/TRAP1

Hintergrund:

Synonyms: HSP75, HSP 75, HSP90L, TRAP-1, Heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, Tumor necrosis factor type 1 receptor-associated protein, TRAP1

Background: Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, most likely through stabilization of mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA.

Gen-ID: 10131

UniProt: Q12931