ARFIP2 Antikörper (AA 221-341) (Cy7)

Produktnummer ABIN686593

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ARFIP2 in WB, IF (cc) und IF (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ARFIP2 Antikörper (AA 221-341) (Cy7) (ABIN686593)

Target: ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARFIP2 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-ARFIP2 Antikörper (Cy7)

Bindungsspezifität: AA 221-341

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Arfaptin 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu ARFIP2

Target: ARFIP2 (ADP-Ribosylation Factor Interacting Protein 2 (ARFIP2))

Andere Bezeichnung: Arfaptin 2

Hintergrund:

Synonyms: ARFIP2, arfaptin 2, ADP-ribosylation factor interacting protein 2, Partner of RAC1, POR1, ARFP2_HUMAN .

Background: ARFIP2 is a ubiquitously expressed protein implicated in mediating cross talk between RAC and ARF small GTPases. It has been shown that ARFIP2 binds specifically to GTP-bound ARF1 and ARF6, but binds to Rac-GTP and Rac-GDP with similar affinities. The X-ray structure of arfaptin reveals an elongated, crescent-shaped dimer of 3-helix coiled-coils. Structures of arfaptin with Rac bound to either GDP or the slowly hydrolysable analog GMPPNP show that the switch regions adopt similar conformations in both complexes.

Gen-ID: 23647