BMP4 Antikörper (AA 251-350)

Produktnummer ABIN685642

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BMP4 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Maus und Schaf und wurde in 1 Publikation erwähnt.

Kurzübersicht für BMP4 Antikörper (AA 251-350) (ABIN685642)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reaktivität: Maus, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BMP4 Antikörper

Bindungsspezifität: AA 251-350

Kreuzreaktivität: Maus, Schaf

Homologie: Human,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from rat BMP4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-BMP4 Antikörper (ABIN685642)

Wang, Zhao, Wang: "Umbilical cord blood cells regulate the differentiation of endogenous neural stem cells in hypoxic ischemic neonatal rats via the hedgehog signaling pathway." in: Brain research, Vol. 1560, pp. 18-26, (2014) (PubMed).

Details zu BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Andere Bezeichnung: BMP4

Hintergrund:

Synonyms: BMP 4, BMP2B, BMP2B1, Bone morphogenetic protein 4, DVR4, ZYME, BMP4_HUMAN, BMP-4, Bone morphogenetic protein 2B, BMP-2B.

Background: BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. Proteins of the TGF beta superfamily are disulfide-linked dimers composed of two 12-15 kDa polypeptide chains. As implied by their name, BMPs initiate, promote and regulate bone development, growth, remodeling and repair. Smad1 translocation to the nucleus is observed after the addition of BMP4 (also designated BMP2B), suggesting that BMP4 may play a role in activation of the Smad pathway. BMP is secreted into the extracellular matrix.

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development