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ITGAV/ITGB5 Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ITGAV/ITGB5 in FACS, IF (cc), IF (p), ELISA, IHC (fro) und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 3+ Publikationen erwähnt.
Produktnummer ABIN685372

Kurzübersicht für ITGAV/ITGB5 Antikörper (ABIN685372)

Target

ITGAV/ITGB5 (Integrin alpha V, Integrin beta 5 (ITGAV/ITGB5))

Reaktivität

  • 23
  • 15
  • 4
Human, Maus

Wirt

  • 15
  • 8
Kaninchen

Klonalität

  • 15
  • 8
Polyklonal

Konjugat

  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ITGAV/ITGB5 Antikörper ist unkonjugiert

Applikation

  • 21
  • 12
  • 12
  • 9
  • 7
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Kreuzreaktivität

    Human, Maus

    Homologie

    Rat

    Aufreinigung

    Purified by Protein A.

    Immunogen

    KLH conjugated synthetic peptide derived from human Integrin beta 5 and Integrin alpha V

    Isotyp

    IgG
  • Applikationshinweise

    ELISA 1:500-1000
    FCM 1:20-100
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 μg/μL

    Buffer

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    Haltbarkeit

    12 months
  • Bian, Ma, Jain, Crane, Kebaish, Wan, Zhang, Edward Guo, Sponseller, Séguin, Riley, Wang, Cao: "Mechanosignaling activation of TGFβ maintains intervertebral disc homeostasis." in: Bone research, Vol. 5, pp. 17008, (2017) (PubMed).

    Chen, Zheng, Liu, Shi, Qi: "Periostin activates pathways involved in epithelial-mesenchymal transition in adamantinomatous craniopharyngioma." in: Journal of the neurological sciences, Vol. 360, pp. 49-54, (2016) (PubMed).

    Mondal, Barui, Chaudhuri: "The relationship between the cyclic-RGDfK ligand and ?v?3 integrin receptor." in: Biomaterials, Vol. 34, Issue 26, pp. 6249-60, (2013) (PubMed).

  • Target

    ITGAV/ITGB5 (Integrin alpha V, Integrin beta 5 (ITGAV/ITGB5))

    Andere Bezeichnung

    Integrin Alpha V + Beta 5

    Hintergrund

    Synonyms: CD51, MSK8, VNRA, VTNR, Integrin alpha-V, Vitronectin receptor subunit alpha, ITGAV

    Background: The alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.

    Gen-ID

    3685

    UniProt

    P06756
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