CEBPA Antikörper (pSer21)

Produktnummer ABIN683548

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CEBPA in ELISA, IF (cc), IF (p) und IHC (fro). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CEBPA Antikörper (pSer21) (ABIN683548)

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPA Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CEBPA Antikörper

Bindungsspezifität: pSer21

Homologie: Human,Mouse,Rat,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human CDBP alpha around the phosphorylation site of Ser21

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Andere Bezeichnung: CEBP alpha

Hintergrund:

Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch 5, C/EBP alpha, CAP4, Caspase 8 precursor, CCAAT Enhancer Binding Protein alpha, CEBP, CEBP A, CEBP alpha, CEBPA, FADD homologous ICE/CED 3 like protease, FADD like ICE, FLICE, ICE like apoptotic protease 5, ICE8, MACH, MCH5, MORT1 associated CED 3 homolog, CEBPA_HUMAN.

Background: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. Mutations in this gene are frequently found in acute myeloid leukemia (AML).

Gen-ID: 1050

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation