beta 2 Adrenergic Receptor Antikörper (pSer346)

Produktnummer ABIN682723

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch beta 2 Adrenergic Receptor in IHC (p), IF (p), IHC (fro) und IF (cc). Es zeigt Reaktivität gegenüber Proben von Human.Es wurde in 1 Publikation zitiert.

Kurzübersicht für beta 2 Adrenergic Receptor Antikörper (pSer346) (ABIN682723)

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser beta 2 Adrenergic Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-beta 2 Adrenergic Receptor Antikörper

Bindungsspezifität: pSer346

Verwendungszweck: phospho-ADRB2 (Ser346) Polyclonal Antibody

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Sheep,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human ADRB2 around the phosphorylation site of Ser346

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-beta 2 Adrenergic Receptor Antikörper (ABIN682723)

Yu, Gratzke, Wang, Herlemann, Strittmatter, Rutz, Stief, Hennenberg: "Inhibition of prostatic smooth muscle contraction by the inhibitor of G protein-coupled receptor kinase 2/3, CMPD101." in: European journal of pharmacology, Vol. 831, pp. 9-19, (2018) (PubMed).

Details zu beta 2 Adrenergic Receptor

Target: beta 2 Adrenergic Receptor (ADRB2) (Adrenergic, beta-2-, Receptor, Surface (ADRB2))

Andere Bezeichnung: ADRB2

Hintergrund:

Synonyms: BAR, B2AR, ADRBR, ADRB2R, BETA2AR, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor, ADRB2

Background: Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Gen-ID: 154

UniProt: P07550

Pathways: cAMP Metabolic Process, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Brown Fat Cell Differentiation