HTR2C Antikörper (AA 311-410)

Produktnummer ABIN682273

Produktdetails anti-HTR2C Antikörper

Target: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Bindungsspezifität: AA 311-410

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HTR2C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human 5HTR2C

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu HTR2C

Target: HTR2C (5-Hydroxytryptamine (serotonin) Receptor 2C (HTR2C))

Andere Bezeichnung: 5HTR2C (HTR2C Produkte)

Synonyme: 5-HT2C antikoerper, 5-HTR2C antikoerper, HTR1C antikoerper, 5-HT2cR antikoerper, 5HT1c antikoerper, Htr1c antikoerper, SR1 antikoerper, 5HT-1C antikoerper, 5HT2C antikoerper, 5-HT-2C antikoerper, 5-ht2cr antikoerper, si:dkey-24g18.2 antikoerper, 5ht2c antikoerper, 5HTR2C antikoerper, 5-hydroxytryptamine receptor 2C antikoerper, 5-hydroxytryptamine (serotonin) receptor 2C antikoerper, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled S homeolog antikoerper, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled-like 1 antikoerper, 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled antikoerper, HTR2C antikoerper, Htr2c antikoerper, htr2c.S antikoerper, htr2cl1 antikoerper, LOC407134 antikoerper

Hintergrund:

Synonyms: 5 Hydroxytryptamine 2C receptor, 5-HT-1C, 5-ht-1c receptor, 5-HT-2C, 5-HT1C, 5-HT2C, 5-HTR2C, 5-hydroxytryptamine serotonin receptor 2C, G protein-coupled, 5-hydroxytryptamine receptor 1C, 5-hydroxytryptamine receptor 2C, 5HT1C, 5HT2C, 5HT2C_HUMAN, 5HTR2C, 5Hydroxytryptamine 2C receptor, Htr1c, HTR2C, serotonin 1c receptor, serotonin 2c receptor, Serotonin 5-HT-2C receptor, Serotonin receptor 2C.

Background: Serotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. This gene encodes the 2C subtype of serotonin receptor and its mRNA is subject to multiple RNA editing events, where genomically encoded adenosine residues are converted to inosines. RNA editing is predicted to alter amino acids within the second intracellular loop of the 5-HT2C receptor and generate receptor isoforms that differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in patterns of 5-HT2C editing in depressed suicide victims. [provided by RefSeq, Jul 2008].

Gen-ID: 3358

Pathways: Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour