OXSR1 Antikörper (AA 201-300)

Produktnummer ABIN681808

Produktdetails anti-OXSR1 Antikörper

Target: OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OXSR1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OXSR1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu OXSR1

Target: OXSR1 (Oxidative-Stress Responsive 1 (OXSR1))

Andere Bezeichnung: OXSR1 (OXSR1 Produkte)

Synonyme: OSR1 antikoerper, C20orf111 antikoerper, HSPC207 antikoerper, Osr1 antikoerper, Perit1 antikoerper, dJ1183I21.1 antikoerper, zgc:55494 antikoerper, zgc:77321 antikoerper, OXSR1 antikoerper, 2210022N24Rik antikoerper, 2810422B09Rik antikoerper, AI462649 antikoerper, AW209236 antikoerper, mKIAA1101 antikoerper, odd1 antikoerper, osr1 antikoerper, wu:fb77f12 antikoerper, zgc:165661 antikoerper, oxidative stress responsive 1 antikoerper, oxidative stress responsive serine rich 1 antikoerper, oxidative stress responsive 1b antikoerper, serine/threonine-protein kinase OSR1 antikoerper, odd-skipped related transciption factor 1 antikoerper, oxidative-stress responsive 1 antikoerper, oxidative stress responsive 1a antikoerper, OXSR1 antikoerper, OSER1 antikoerper, oxsr1b antikoerper, CpipJ_CPIJ015177 antikoerper, Tsp_00299 antikoerper, OSR1 antikoerper, Oxsr1 antikoerper, LOC106505565 antikoerper, oxsr1 antikoerper, oxsr1a antikoerper

Hintergrund:

Synonyms: KIAA1101, OSR 1, OSR1, Oxidative stress responsive 1, Oxidative stress responsive 1 protein, OXSR 1, Serine/threonine protein kinase OSR1.

Background: OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses, notably sorbitol and, to a lesser extent, NaCl. OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1. Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK. OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT. OXSR1 may have a role in regulating the actin cytoskeleton.

Gen-ID: 9943

Pathways: Tube Formation