Vdcc-L alpha (AA 1001-1100) Antikörper

Produktnummer ABIN680983

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Vdcc-L alpha in IF (p), IF (cc), ELISA, IHC (fro) und IHC (p). Es zeigt Reaktivität gegenüber Proben von Maus und Ratte.Es wurde in 1 Publikation zitiert.

Kurzübersicht für Vdcc-L alpha (AA 1001-1100) Antikörper (ABIN680983)

Target: Vdcc-L alpha

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: AA 1001-1100

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VDCC-L alpha

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen

Lobeck, Donnelly, Dupree, Mahe, McNeal, Mohanty, Tiao: "Rhesus rotavirus VP6 regulates ERK-dependent calcium influx in cholangiocytes." in: Virology, Vol. 499, pp. 185-195, (2016) (PubMed).

Antigendetails

Target: Vdcc-L alpha

Hintergrund:

Synonyms: VDCC-L alpha 1, L-VDCC alpha 1, Voltage dependent calcium channel subunit alpha 1, CACNL1A1, Alpha1c L-type VDCC, CACBR, CACH2, CACN2, CACNA1C, CACNL1A1, CaV1.2, CCHL1A1, L-TYPE CALCIUM CHANNEL ALPHA1C, L-type voltage dependent calcium channel a1, L-TYPE VOLTAGE DEPENDENT CALCIUM CHANNEL ALPHA 1.2, L-VDCC ALPHA1, LOC283439, MGC120730, RATIVS302, TS, CAC1C_HUMAN.

Background: This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. [provided by RefSeq]

Gen-ID: 775