ITK Antikörper (AA 101-200)

Produktnummer ABIN680653

This anti-ITK antibody (ABIN680653) is a Rabbit Polyclonal antibody detecting ITK in ELISA, IF (cc), IF (p), IHC (p), IHC (fro). Suitable for Human.

Kurzübersicht für ITK Antikörper (AA 101-200) (ABIN680653)

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ITK Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-ITK Antikörper

Bindungsspezifität: AA 101-200

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ITK/PSCTK2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu ITK

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Andere Bezeichnung: ITK

Hintergrund:

Synonyms: EMT, Homolog of mouse T cell itk/tsk, IL2 inducible T cell kinase, Kinase EMT, LYK, MGC126257, MGC126258, PSCTK 2, PSCTK2, T cell specic kinase, TSK, Tyrosine protein kinase, Tyrosine protein kinase ITK/TSK, Tyrosine protein kinase Lyk.

Background: ITK is a T cell signaling protein. The Tec family of non receptor tyrosine kinases is composed of six proteins designated Tec, ITK (also known as Emt or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini. ITK associates with CD28 and becomes activated subsequent to CD28 ligation.

Gen-ID: 3702

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung