GCKR Antikörper (AA 261-360)

Produktnummer ABIN679883

This anti-GCKR antibody (ABIN679883) is a Rabbit Polyclonal antibody detecting GCKR in WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro). Suitable for Human, Mouse.

Kurzübersicht für GCKR Antikörper (AA 261-360) (ABIN679883)

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCKR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-GCKR Antikörper

Bindungsspezifität: AA 261-360

Kreuzreaktivität: Human, Maus

Homologie: Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GKRP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GCKR

Target: GCKR (Glucokinase (Hexokinase 4) Regulator (GCKR))

Andere Bezeichnung: GKRP

Hintergrund:

Synonyms: FGQTL5, GCK, GCKR, GCKR_HUMAN, GKRP, GLRE, glucokinase hexokinase 4 regulator, Glucokinase, Glucokinase regulator, Glucokinase regulatory protein, Hexokinase type IV, Hexokinase-4, Hexokinase-D, HK IV, HK4, OTTHUMP00000158533.

Background: GCKR is a subfamily member of the SIS (Sugar ISomerase) family of proteins. It is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young.

Gen-ID: 2646

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus