Integrin, alpha E2 (AA 1101-1179) Antikörper

Produktnummer ABIN678758

Der Kaninchen Polyklonal anti-Integrin, alpha E2 Antikörper wird verwendet zum Nachweis von Integrin, alpha E2 in Proben von Ratte, Human und Maus. Er wurde validiert für FACS, ELISA, IF (cc), IF (p), IHC (fro) und WB.

Kurzübersicht für Integrin, alpha E2 (AA 1101-1179) Antikörper (ABIN678758)

Target: Integrin, alpha E2

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Flow Cytometry (FACS), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)

Produktdetails

Bindungsspezifität: AA 1101-1179

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Integrin alpha-E heavy chain

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: Integrin, alpha E2

Hintergrund:

Synonyms: Itgae, A530055J10, alpha-E1, alpha-M290, aM290, CD103, MGC183601, antigen CD103, human mucosal lymphocyte antigen 1, alpha polypeptide.ITAE_HUMAN, Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, Integrin alpha-E heavy chain.

Background: CD103/Integrin alpha E is a new member of the integrin series of adhesion molecules containing the beta7 subunit. This antigen defines a developmentally important subset of T cells, namely mucosal T cells including all IEL (intraepithelial lymphocytes) and ~20 % of lamina propria T cells. Expression of CD103 is more restricted outside these mucosal organs, appearing at lower levels on T cell subsets of the lymph node, dendritic epidermis and periphery. In non-epithelial CD103+ T cells there is a bias toward expression on CD8+ cells. Integrin alpha E is a heterodimer comprising a 150 kDa alpha chain and a 120 kDa beta chain. Integrin alpha E is expressed by approximately 1 % of peripheral blood lymphocytes, activated T lymphocytes and by hairy cell leukaemia cells. The antigen is also expressed by intraepithelial lymphocytes.

Molekulargewicht: 128kDa

Gen-ID: 3682