ITGAV/ITGB1 Antikörper (PE-Cy7)
Kurzübersicht für ITGAV/ITGB1 Antikörper (PE-Cy7) (ABIN676731)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- Integrin Alpha V + Beta 1 Polyclonal Antibody, PE-Cy7 Conjugated
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Kreuzreaktivität
- Human, Ratte
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Homologie
- Mouse,Dog,Cow,Sheep,Pig,Horse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Mixed KLH conjugated syntheticpeptides for human Integrin Alpha V and human Integrin Beta1
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000), FCM(1:20-100)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- ITGAV/ITGB1 (Integrin alpha V, Integrin beta 1 (ITGAV/ITGB1))
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Sub Type
- Cocktail
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Hintergrund
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Synonyms: Integrin alpha-V: Integrin alpha-V, Vitronectin receptor subunit alpha, CD51 Integrin beta-1: Fibronectin receptor subunit beta, Glycoprotein IIa, GPIIA, VLA-4 subunit beta, CD29
Background: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. Integrin alpha-V/beta-1 is a receptor for vitronectin. Beta-1 integrins recognize the sequence R-G-D in a wide array of ligands. Isoform 2 interferes with isoform 1 resulting in a dominant negative effect on cell adhesion and migration (in vitro).
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Molekulargewicht
- 114kDa
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Gen-ID
- 3685
Target
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