UCP2 Antikörper (AA 201-309)
Kurzübersicht für UCP2 Antikörper (AA 201-309) (ABIN675428)
Target
Alle UCP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 201-309
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Verwendungszweck
- UCP-2 Polyclonal Antibody
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Kreuzreaktivität
- Human, Maus, Ratte
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Homologie
- Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from Mouse UCP-2 (Mitochondrial intermembrane space domain)
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000),
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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: "Methylglyoxal Impairs Insulin Secretion of Pancreatic β-Cells through Increased Production of ROS and Mitochondrial Dysfunction Mediated by Upregulation of UCP2 and MAPKs." in: Journal of diabetes research, Vol. 2016, pp. 2029854, (2016) (PubMed).
: "Peroxisome proliferator-activated receptors ?/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status ..." in: Journal of neuroinflammation, Vol. 9, pp. 184, (2012) (PubMed).
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- UCP2 (Uncoupling Protein 2 (Mitochondrial, Proton Carrier) (UCP2))
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Andere Bezeichnung
- UCP-2
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Hintergrund
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Synonyms: Slc25a8, Mitochondrial uncoupling protein 2, UCP 2, Solute carrier family 25 member 8, UCPH, Ucp2
Background: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity).
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Gen-ID
- 22228
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UniProt
- P70406
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Pathways
- Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Proton Transport
Target
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