PDGF-BB Homodimer (AA 151-241) Antikörper

Produktnummer ABIN674874

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro). Geeignet für Human, Maus, Ratte und Huhn. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für PDGF-BB Homodimer (AA 151-241) Antikörper (ABIN674874)

Target: PDGF-BB Homodimer

Reaktivität: Human, Maus, Ratte, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails

Bindungsspezifität: AA 151-241

Kreuzreaktivität: Huhn, Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PDGF-B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen

Cipriani, Di Benedetto, Dietrich, Ruscitti, Liakouli, Carubbi, Pantano, Berardicurti, Sgonc, Giacomelli: "Searching for a good model for systemic sclerosis: the molecular profile and vascular changes occurring in UCD-200 chickens strongly resemble the early phase of human systemic sclerosis." in: Archives of medical science : AMS, Vol. 12, Issue 4, pp. 828-43, (2016) (PubMed).

Antigendetails

Target: PDGF-BB Homodimer

Andere Bezeichnung: PDGFBB

Hintergrund:

Synonyms: PDGF BB, PDGF-BB, platelet derived growth factor-BB, Becaplermin, C sis, FLJ12858, Oncogene SIS, PDG B chain, PDGB, PDGF 2, PDGF B, PDGF B chain, PDGF2, PDGFB, PDGFB/COL1A1 fusion gene, Platelet derived growth factor 2, Platelet derived growth factor B chain, Platelet derived growth factor beta, Platelet derived growth factor beta polypeptide, Simian sarcoma viral v sis oncogene homolog, SIS, SSV, V sis platelet derived growth factor beta polypeptide.

Background: Platelet Derived Growth Factor (PDGF) is the major serum mitogen for cells of mesenchymal origin in humans. The biologically active protein is a dimer composed of two related polypeptides designated A and B, the dimers being connected by disulfide bonds. The PDGF protein has been implicated both directly as well as indirectly in several pathological states including neoplasia, arthritis, arteriosclerosis and bone marrow sclerosis.

Gen-ID: 5155