CEACAM3 Antikörper (AA 177-226)

Produktnummer ABIN6746759

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CEACAM3 in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für CEACAM3 Antikörper (AA 177-226) (ABIN6746759)

Target: CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEACAM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CEACAM3 Antikörper

Bindungsspezifität: AA 177-226

Spezifität: Human CEACAM3

Homologie: Percent identity by BLAST analysis:

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa177-226 of human CEACAM3 (P40198, NP_001806). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla (100%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Referenzen für anti-CEACAM3 Antikörper (ABIN6746759)

Li, Trudel, Wogan: "Nitric oxide-induced genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells expressing wild-type and mutant p53." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 16, pp. 10364-9, (2002) (PubMed).

Cain, Brown, Langlais, Cohen: "Caspase activation involves the formation of the aposome, a large (approximately 700 kDa) caspase-activating complex." in: The Journal of biological chemistry, Vol. 274, Issue 32, pp. 22686-92, (1999) (PubMed).

Hu, Benedict, Ding, Núñez: "Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis." in: The EMBO journal, Vol. 18, Issue 13, pp. 3586-95, (1999) (PubMed).

Soengas, Alarcón, Yoshida, Giaccia, Hakem, Mak, Lowe: "Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition." in: Science (New York, N.Y.), Vol. 284, Issue 5411, pp. 156-9, (1999) (PubMed).

Details zu CEACAM3

Target: CEACAM3 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3))

Andere Bezeichnung: CD66d / CEACAM3

Hintergrund: Name/Gene ID: CEACAM3
Family: CEA

Synonyms: CEACAM3, Carcinoembryonic antigen CGM1, CGM1, CD66d antigen, CEA, W264, W282, CD66D

Gen-ID: 1084

NCBI Accession: NP_001806

UniProt: P40198