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IRGC Antikörper (AA 73-122)

Der Kaninchen Polyklonal Anti-IRGC-Antikörper wurde für WB validiert. Er ist geeignet, IRGC in Proben von Human, Ratte, Maus und Hund zu detektieren. Es sind 3+ Publikationen verfügbar.
Produktnummer ABIN6746505

Kurzübersicht für IRGC Antikörper (AA 73-122) (ABIN6746505)

Target

Alle IRGC Antikörper anzeigen
IRGC (Immunity-Related GTPase Family, Cinema (IRGC))

Reaktivität

  • 28
  • 20
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus, Hund

Wirt

  • 28
Kaninchen

Klonalität

  • 28
Polyklonal

Konjugat

  • 9
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IRGC Antikörper ist unkonjugiert

Applikation

  • 28
  • 14
  • 13
  • 13
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 6
    • 4
    • 2
    • 1
    AA 73-122

    Spezifität

    Mouse IRGC

    Homologie

    Percent identity by BLAST analysis: Mouse (100%).

    Aufreinigung

    Immunoaffinity purified

    Immunogen

    Synthetic peptide located between aa73-122 of mouse Irgc1 (Q8C262, NP_950178). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Mouse, Rat, Elephant, Panda, Dog (100%), Galago, Marmoset, Bovine, Bat, Horse, Pig, Guinea pig (92%).

    Type of Immunogen: Synthetic peptide
  • Applikationshinweise

    Approved: WB (1 μg/mL)

    Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

    Kommentare

    Target Species of Antibody: Mouse

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Distilled water

    Konzentration

    Lot specific

    Buffer

    Lyophilized from PBS with 2 % sucrose

    Handhabung

    Avoid repeat freeze-thaw cycles.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
    Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
  • Bolton, Anthony, Perry: "Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo." in: Neuroscience, Vol. 86, Issue 4, pp. 1245-57, (1998) (PubMed).

    Fanning, Jameson, Jesaitis, Anderson: "The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton." in: The Journal of biological chemistry, Vol. 273, Issue 45, pp. 29745-53, (1998) (PubMed).

    Ando-Akatsuka, Saitou, Hirase, Kishi, Sakakibara, Itoh, Yonemura, Furuse, Tsukita: "Interspecies diversity of the occludin sequence: cDNA cloning of human, mouse, dog, and rat-kangaroo homologues." in: The Journal of cell biology, Vol. 133, Issue 1, pp. 43-7, (1996) (PubMed).

  • Target

    IRGC (Immunity-Related GTPase Family, Cinema (IRGC))

    Andere Bezeichnung

    IRGC1 / CINEMA

    Hintergrund

    Name/Gene ID: IRGC

    Synonyms: IRGC, CINEMA, Iigp5, IFGGE, Interferon inducible GTPase 5, IRGC1, Interferon-inducible GTPase 5, R30953_1

    Gen-ID

    56269

    NCBI Accession

    NP_950178

    UniProt

    Q6NXR0
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