FMR1 Antikörper (AA 421-470)

Produktnummer ABIN6746187

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FMR1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Affe, Kaninchen, Schwein, Rind (Kuh), Fledermaus, Meerschweinchen und Huhn. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für FMR1 Antikörper (AA 421-470) (ABIN6746187)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reaktivität: Human, Maus, Ratte, Hund, Affe, Kaninchen, Schwein, Rind (Kuh), Fledermaus, Meerschweinchen, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FMR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FMR1 Antikörper

Bindungsspezifität: AA 421-470

Spezifität: Rat FMR1

Homologie: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Pig, Guinea pig, Chicken (100%) Xenopus (92%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa421-470 of rat Fmr1 (Q80WE1, NP_434691). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Pig, Guinea pig, Turkey, Chicken (100%), Platypus, Xenopus (92%), Zebra finch (91%), Opossum (84%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Referenzen für anti-FMR1 Antikörper (ABIN6746187)

Devarajan, De Leon, Talasazan, Schoenfeld, Davidowitz, Burk: "The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 40599-605, (2001) (PubMed).

Anderson, Teutsch, Dong, Wortis: "An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 20, pp. 10966-71, (1996) (PubMed).

Details zu FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Andere Bezeichnung: FMR1 / FMRP

Hintergrund: Name/Gene ID: FMR1

Synonyms: FMR1, FMRP, POF, Protein FMR-1, Premature ovarian failure 1, Fragile X mental retardation 1, FRAXA, POF1

Gen-ID: 2332

NCBI Accession: NP_434691

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development