FMR1 Antikörper (AA 421-470)

Produktnummer ABIN6746187

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FMR1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Affe, Kaninchen, Schwein, Rind (Kuh), Fledermaus, Meerschweinchen und Huhn und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für FMR1 Antikörper (AA 421-470) (ABIN6746187)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reaktivität: Human, Maus, Ratte, Hund, Affe, Kaninchen, Schwein, Rind (Kuh), Fledermaus, Meerschweinchen, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FMR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FMR1 Antikörper

Bindungsspezifität: AA 421-470

Spezifität: Rat FMR1

Homologie: Percent identity by BLAST analysis: Human, Mouse, Rat, Dog, Bovine, Rabbit, Pig, Guinea pig, Chicken (100%) Xenopus (92%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa421-470 of rat Fmr1 (Q80WE1, NP_434691). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Galago, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Pig, Guinea pig, Turkey, Chicken (100%), Platypus, Xenopus (92%), Zebra finch (91%), Opossum (84%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: WB (0.2 - 1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Distilled water

Konzentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Referenzen für anti-FMR1 Antikörper (ABIN6746187)

Devarajan, De Leon, Talasazan, Schoenfeld, Davidowitz, Burk: "The von Hippel-Lindau gene product inhibits renal cell apoptosis via Bcl-2-dependent pathways." in: The Journal of biological chemistry, Vol. 276, Issue 44, pp. 40599-605, (2001) (PubMed).

Anderson, Teutsch, Dong, Wortis: "An essential role for Bruton's [corrected] tyrosine kinase in the regulation of B-cell apoptosis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 20, pp. 10966-71, (1996) (PubMed).

Details zu FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Andere Bezeichnung: FMR1 / FMRP

Hintergrund: Name/Gene ID: FMR1

Synonyms: FMR1, FMRP, POF, Protein FMR-1, Premature ovarian failure 1, Fragile X mental retardation 1, FRAXA, POF1

Gen-ID: 2332

NCBI Accession: NP_434691

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development