CHRM3 Antikörper (AA 481-589)

Produktnummer ABIN674484

Dieses Anti-CHRM3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CHRM3 in WB, ELISA, IHC (p), IF (cc), IF (p) und IHC (fro). Geeignet für Human, Ratte und Maus. Dieses Primary Antibody wurde in 3+ Publikationen zitiert.

Kurzübersicht für CHRM3 Antikörper (AA 481-589) (ABIN674484)

Target: CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRM3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-CHRM3 Antikörper

Bindungsspezifität: AA 481-589

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Chrm3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CHRM3 Antikörper (ABIN674484)

Zhao, Yang, Chen, Wang, Zhang, Zhang: "Expression of M3 acetylcholine receptor in asthmatic mice and bronchial airway remodeling prediction." in: Genetics and molecular research : GMR, Vol. 15, Issue 3, (2016) (PubMed).

Ozgun-Acar, Celik-Turgut, Gazioglu, Kolak, Ozbal, Ergur, Arslan, Sen, Topcu: "Capparis ovata treatment suppresses inflammatory cytokine expression and ameliorates experimental allergic encephalomyelitis model of multiple sclerosis in C57BL/6 mice." in: Journal of neuroimmunology, Vol. 298, pp. 106-16, (2016) (PubMed).

Chen, Li, Zhang, Zhai, Gong, Qiang, Xue: "An ENU-induced mutation of Nrg1 causes dilated pupils and a reduction in muscarinic receptors in the sphincter pupillae." in: PLoS ONE, Vol. 6, Issue 9, pp. e25176, (2011) (PubMed).

Details zu CHRM3

Target: CHRM3 (Cholinergic Receptor, Muscarinic 3 (CHRM3))

Andere Bezeichnung: Chrm3

Hintergrund:

Synonyms: M3, M3R, Chrm-3, Muscarinic acetylcholine receptor M3, Mm3 mAChR, Chrm3

Background: The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.

Gen-ID: 12671

UniProt: Q9ERZ3

Pathways: Synaptic Membrane